How to use Alphafold 2? How does it work
There are multiple techniques to determine 3D structure of Protein:
X Ray Crystallography
NMR
Cryo-electron Microscopy
All these techniques are very time consuming and scientists were looking for new methods
Recently Deepmind introduced Alphafold, which can predict the 3D protein structure with high accuracy
On 15th July 2021 Deepmind published a paper on Alphafold 2 algorithm, the code was released free on github for the scientific community
To use Alphafold 2, Biologists needed computers with very high computing power, this was resolved by Deepmind partnering with EMBL
To search for a protein sequence, one can use Protein Similarity Search by EMBL - https://www.ebi.ac.uk/Tools/sss/ncbiblast/
Its a very simple interface to use, and get the desired protein structures
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