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About Us

 

LEADING THE DISCOVERY
of Allosteric Binding Sites to Create New Medicines

Gain Therapeutics is redefining drug discovery with its SEE-Tx™ target identification platform.

By identifying and optimizing allosteric binding sites that have never before been targeted, Gain is unlocking new treatment options for difficult-to-treat disorders characterized by protein misfolding, including lysosomal storage disorders.

Protein misfolding is an underlying biological issue of many diseases, including lysosomal storage disorders and some neurodegenerative diseases such as Parkinson’s disease. When a protein misfolds, its 3D structure is disrupted and it can no longer function properly. While some treatments are available for these types of disorders, they have significant limitations.

Gain was originally established in 2017 with the support of its founders and institutional investors such as TiVenture, 3B Future Health Fund (previously known as Helsinn Investment Fund) and VitaTech. It has been awarded funding support from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and The Silverstein Foundation for Parkinson’s with GBA, as well as from the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and Innosuisse. In July 2020, Gain Therapeutics, Inc. completed a share exchange with Gain Therapeutics SA, a Swiss corporation, whereby GT Gain Therapeutics SA became a wholly owned subsidiary of Gain Therapeutics, Inc.

 
leadership team

Eric I. Richman

Chief Executive Officer

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Manolo Bellotto, Ph.D.

General Manager and President

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Matthias Alder

Chief Operating Officer

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Salvatore Calabrese

Chief Financial Officer

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Xavier Barril, Ph.D.

Chief Scientific Officer

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Ana Maria Garcia-Collazo, Ph.D.

VP Research & Site Leader

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Elena Cubero-Jorda, Ph.D.

Director Computational Chemistry

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Natália Pérez-Carmona, Ph.D.

Director Biology

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Terenzio Ignoni, Pharm.D.

SVP Quality and CMC

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Roberto Maj, Pharm.D.

VP Development

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Khalid Islam, Ph.D.

Chairman

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Eric I. Richman

Chief Executive Officer

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Jeffrey Riley

Independent Member

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Dov Goldstein, M.D.

Independent Member

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Gwen Melincoff

Independent Member

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Claude Nicaise, M.D.

Independent Member

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Hans Peter Hasler

Independent Member

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Luca Benatti, Ph.D.

SAB Chairman

Samuel Broder, M.D.

Lorenzo Leoni, Ph.D.

Joanne Taylor, Ph.D.

Michel Vellard, Ph.D.

 

 
 
 

Research and Development Collaborations

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Grants

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Patient Associations

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Centers of Research, Translational Science & Clinical Excellence

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